Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FBXW5F-box and WD repeat domain containing 5. (641 aa)    
Predicted Functional Partners:
CUL1
Cullin 1; Belongs to the cullin family.
    
 0.959
DDB1
Damage specific DNA binding protein 1.
    
 0.946
RBX1
Ring-box 1.
    
 0.932
CUL4A
Cullin 4A; Belongs to the cullin family.
    
 0.924
SEC23B
Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.
    
 
 0.910
ENSCATP00000020004
Uncharacterized protein; Belongs to the SKP1 family.
    
 0.883
SKP1
S-phase kinase associated protein 1; Belongs to the SKP1 family.
    
 0.883
CUL4B
Cullin 4B; Belongs to the cullin family.
    
 0.829
TSC2
TSC complex subunit 2.
    
 
 0.773
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.768
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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