Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FGD6FYVE, RhoGEF and PH domain containing 6. (1431 aa)    
Predicted Functional Partners:
DBNL
Drebrin like.
    
 
 0.695
UHMK1
U2AF homology motif kinase 1.
      
 0.659
NELL1
Neural EGFL like 1.
      
 0.601
GCSAM
Germinal center associated signaling and motility.
      
 0.584
TMEM14A
Transmembrane protein 14A.
      
 0.574
SMDT1
Single-pass membrane protein with aspartate rich tail 1.
    
 0.518
ARHGEF16
Rho guanine nucleotide exchange factor 16.
   
 
 0.511
SYT1
Synaptotagmin 1.
      
 0.510
DBN1
Drebrin 1.
    
 
 0.505
MOCOS
Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.
      
 0.500
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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