Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
MAPK6Mitogen-activated protein kinase 6. (721 aa)    
Predicted Functional Partners:
MAPKAPK5
MAPK activated protein kinase 5.
    
 0.976
MAPK4
Mitogen-activated protein kinase 4.
   
 
  0.973
HERC2
HECT and RLD domain containing E3 ubiquitin protein ligase 2.
    
 0.891
NEURL4
Neuralized E3 ubiquitin protein ligase 4.
    
 
 0.886
FOS
Fos proto-oncogene, AP-1 transcription factor subunit.
    
 0.776
CCND3
Cyclin D3; Belongs to the cyclin family.
    
 0.775
FOSL1
FOS like 1, AP-1 transcription factor subunit.
    
 0.772
FOSB
FosB proto-oncogene, AP-1 transcription factor subunit.
    
 0.772
XPO1
Exportin 1.
    
 0.770
MAPK1
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
    
   0.763
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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