Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
FNTAFarnesyltransferase, CAAX box, alpha. (379 aa)    
Predicted Functional Partners:
FNTB
Protein farnesyltransferase subunit beta; Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.
    
 0.999
PGGT1B
Protein geranylgeranyltransferase type I subunit beta.
    
 0.998
RCE1
Ras converting CAAX endopeptidase 1.
     
 0.975
DHDDS
Alkyl transferase; Belongs to the UPP synthase family.
     
 0.953
PDSS1
Decaprenyl diphosphate synthase subunit 1; Belongs to the FPP/GGPP synthase family.
     
 0.943
PDSS2
Decaprenyl diphosphate synthase subunit 2; Belongs to the FPP/GGPP synthase family.
     
 0.938
GGPS1
Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family.
     
 0.937
ZMPSTE24
CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.
     
 0.934
ENSCATP00000032038
Uncharacterized protein; Belongs to the FPP/GGPP synthase family.
     
 0.933
FDPS
Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family.
     
 0.933
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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