Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SLC12A3Solute carrier family 12 member 3. (1030 aa)    
Predicted Functional Partners:
STK39
Serine/threonine kinase 39.
    
 0.978
OXSR1
Oxidative stress responsive kinase 1.
    
 0.974
WNK4
WNK lysine deficient protein kinase 4.
    
 
 0.766
CLCNKB
Chloride channel protein.
   
  
 0.703
KCNJ1
Potassium voltage-gated channel subfamily J member 1.
   
  
 0.681
WNK1
WNK lysine deficient protein kinase 1.
    
 
 0.681
CLDN16
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
   
  
 0.665
BSND
Barttin CLCNK type accessory beta subunit.
   
  
 0.649
SNX1
Sorting nexin 1.
    
   0.640
WNK3
WNK lysine deficient protein kinase 3.
    
 
 0.635
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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