Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC105576630Ig-like domain-containing protein; Belongs to the MHC class I family. (403 aa)    
Predicted Functional Partners:
B2M
Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
   
 0.978
HLA-E
Major histocompatibility complex, class I, E; Belongs to the MHC class I family.
  
0.947
TAPBP
TAP binding protein.
   
 0.920
CD8A
CD8a molecule.
    
 0.899
LOC105578248
Uncharacterized protein.
    
 0.888
LOC105582733
Uncharacterized protein.
    
 0.888
KLRD1
Killer cell lectin like receptor D1.
    
 0.883
CALR
Calreticulin.
    
 0.823
ENSCATP00000034214
Ig-like domain-containing protein; Belongs to the MHC class I family.
  
 
0.795
PDIA3
Protein disulfide isomerase family A member 3.
    
 0.794
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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