STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARIH2RBR-type E3 ubiquitin transferase. (500 aa)    
Predicted Functional Partners:
CUL5
Cullin 5; Belongs to the cullin family.
    
 0.740
TNF
Tumor necrosis factor; Belongs to the tumor necrosis factor family.
    
 0.608
ELOB
Elongin B.
    
 0.549
BIRC6
Baculoviral IAP repeat containing 6.
    
 0.521
CYLD
CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family.
    
 0.495
NFATC4
Nuclear factor of activated T cells 4.
    
 0.495
IKBKG
Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.
    
 0.489
OPTN
Optineurin.
    
 0.489
TSNARE1
t-SNARE domain containing 1.
      
 0.483
ZNF584
Zinc finger protein 584.
    
 
 0.482
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.