Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GCM1Glial cells missing transcription factor 1. (436 aa)    
Predicted Functional Partners:
GCM2
Glial cells missing transcription factor 2.
  
  
0.910
HTRA4
HtrA serine peptidase 4.
    
 
 0.837
FBXW2
F-box and WD repeat domain containing 2.
    
 
 0.682
HTRA1
HtrA serine peptidase 1.
    
 
 0.680
CREBBP
CREB binding protein.
    
   0.647
SYDE1
Synapse defective Rho GTPase homolog 1.
      
 0.636
SYDE2
Synapse defective Rho GTPase homolog 2.
      
 0.613
CRYAB
Crystallin alpha B; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.
      
 0.595
S100B
S_100 domain-containing protein; Belongs to the S-100 family.
      
 0.590
HTRA2
HtrA serine peptidase 2.
    
 
 0.584
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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