Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DENND2CDENN domain containing 2C. (927 aa)    
Predicted Functional Partners:
RAB9A
RAB9A, member RAS oncogene family.
     
 0.778
C3orf67
Chromosome 3 open reading frame 67.
      
 0.671
RHOBTB3
Rho related BTB domain containing 3.
      
 0.595
RAB35
RAB35, member RAS oncogene family.
    
 0.543
IFT27
Intraflagellar transport 27.
    
 0.543
CHM
Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
   
 
  0.516
AVL9
AVL9 cell migration associated.
      
 0.497
SYTL1
Synaptotagmin like 1.
      
 0.450
NRROS
Negative regulator of reactive oxygen species.
      
 0.449
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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