Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MICU2Mitochondrial calcium uptake 2. (432 aa)    
Predicted Functional Partners:
MICU1
Uncharacterized protein.
    
0.996
MCU
Mitochondrial calcium uniporter.
    
 0.989
SMDT1
Single-pass membrane protein with aspartate rich tail 1.
    
 0.987
MCUB
Mitochondrial calcium uniporter dominant negative beta subunit.
    
 0.973
LOC105583051
Prohibitin.
    
 0.842
TIMM22
Translocase of inner mitochondrial membrane 22.
     
 0.823
TIMM13
Translocase of inner mitochondrial membrane 13; Belongs to the small Tim family.
      
 0.807
NDUFA8
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
      
 0.807
HTRA2
HtrA serine peptidase 2.
      
 0.807
PARL
Rhomboid domain-containing protein.
      
 0.804
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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