TEC protein (Cercocebus atys) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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[Homology]

Score

TEC

Tyrosine-protein kinase. (630 aa)

Predicted Functional Partners:

VAV1

0.993

LCP2

0.987

PLCG2

0.973

PLCG1

0.973

BTK

0.965

ITK

0.958

VAV3

0.954

VAV2

0.952

BLNK

0.945

KIT

0.860

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

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... functional annotations:

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BLNK	BTK	ENSCATP00000035040	ENSCATP00000020405	B cell linker.	Tyrosine-protein kinase.	0.988
BLNK	ITK	ENSCATP00000035040	ENSCATP00000014455	B cell linker.	Tyrosine-protein kinase.	0.551
BLNK	LCP2	ENSCATP00000035040	ENSCATP00000004225	B cell linker.	Lymphocyte cytosolic protein 2.	0.908
BLNK	PLCG1	ENSCATP00000035040	ENSCATP00000022385	B cell linker.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.603
BLNK	PLCG2	ENSCATP00000035040	ENSCATP00000020331	B cell linker.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.975
BLNK	TEC	ENSCATP00000035040	ENSCATP00000001996	B cell linker.	Tyrosine-protein kinase.	0.945
BLNK	VAV1	ENSCATP00000035040	ENSCATP00000018444	B cell linker.	Vav guanine nucleotide exchange factor 1.	0.958
BLNK	VAV2	ENSCATP00000035040	ENSCATP00000025843	B cell linker.	Vav guanine nucleotide exchange factor 2.	0.953
BLNK	VAV3	ENSCATP00000035040	ENSCATP00000002336	B cell linker.	Vav guanine nucleotide exchange factor 3.	0.934
BTK	BLNK	ENSCATP00000020405	ENSCATP00000035040	Tyrosine-protein kinase.	B cell linker.	0.988
BTK	ITK	ENSCATP00000020405	ENSCATP00000014455	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.609
BTK	KIT	ENSCATP00000020405	ENSCATP00000000977	Tyrosine-protein kinase.	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.441
BTK	LCP2	ENSCATP00000020405	ENSCATP00000004225	Tyrosine-protein kinase.	Lymphocyte cytosolic protein 2.	0.985
BTK	PLCG1	ENSCATP00000020405	ENSCATP00000022385	Tyrosine-protein kinase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.983
BTK	PLCG2	ENSCATP00000020405	ENSCATP00000020331	Tyrosine-protein kinase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.995
BTK	TEC	ENSCATP00000020405	ENSCATP00000001996	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.965
BTK	VAV1	ENSCATP00000020405	ENSCATP00000018444	Tyrosine-protein kinase.	Vav guanine nucleotide exchange factor 1.	0.774
BTK	VAV2	ENSCATP00000020405	ENSCATP00000025843	Tyrosine-protein kinase.	Vav guanine nucleotide exchange factor 2.	0.831
BTK	VAV3	ENSCATP00000020405	ENSCATP00000002336	Tyrosine-protein kinase.	Vav guanine nucleotide exchange factor 3.	0.613
ITK	BLNK	ENSCATP00000014455	ENSCATP00000035040	Tyrosine-protein kinase.	B cell linker.	0.551