MAP1LC3A protein (Cercocebus atys) - STRING interaction network

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Score

MAP1LC3A

Microtubule associated protein 1 light chain 3 alpha. (125 aa)

Predicted Functional Partners:

SQSTM1

0.997

ATG7

0.997

ATG3

0.997

ATG5

0.992

ATG4B

0.992

LOC105589083

0.991

NBR1

0.991

ATG12

0.986

MAP1LC3B

0.985

CALCOCO2

0.984

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG12	ATG3	ENSCATP00000039750	ENSCATP00000043402	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy-related protein 3.	0.999
ATG12	ATG4B	ENSCATP00000039750	ENSCATP00000018223	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	0.730
ATG12	ATG5	ENSCATP00000039750	ENSCATP00000018165	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.999
ATG12	ATG7	ENSCATP00000039750	ENSCATP00000022229	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.999
ATG12	LOC105589083	ENSCATP00000039750	ENSCATP00000018627	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Uncharacterized protein.	0.656
ATG12	MAP1LC3A	ENSCATP00000039750	ENSCATP00000002003	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Microtubule associated protein 1 light chain 3 alpha.	0.986
ATG12	MAP1LC3B	ENSCATP00000039750	ENSCATP00000021979	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Uncharacterized protein.	0.980
ATG12	NBR1	ENSCATP00000039750	ENSCATP00000031278	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	ZZ-type domain-containing protein.	0.656
ATG12	SQSTM1	ENSCATP00000039750	ENSCATP00000021260	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Sequestosome 1.	0.790
ATG3	ATG12	ENSCATP00000043402	ENSCATP00000039750	Autophagy-related protein 3.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.999
ATG3	ATG4B	ENSCATP00000043402	ENSCATP00000018223	Autophagy-related protein 3.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	0.865
ATG3	ATG5	ENSCATP00000043402	ENSCATP00000018165	Autophagy-related protein 3.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.999
ATG3	ATG7	ENSCATP00000043402	ENSCATP00000022229	Autophagy-related protein 3.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.997
ATG3	LOC105589083	ENSCATP00000043402	ENSCATP00000018627	Autophagy-related protein 3.	Uncharacterized protein.	0.519
ATG3	MAP1LC3A	ENSCATP00000043402	ENSCATP00000002003	Autophagy-related protein 3.	Microtubule associated protein 1 light chain 3 alpha.	0.997
ATG3	MAP1LC3B	ENSCATP00000043402	ENSCATP00000021979	Autophagy-related protein 3.	Uncharacterized protein.	0.991
ATG3	NBR1	ENSCATP00000043402	ENSCATP00000031278	Autophagy-related protein 3.	ZZ-type domain-containing protein.	0.519
ATG3	SQSTM1	ENSCATP00000043402	ENSCATP00000021260	Autophagy-related protein 3.	Sequestosome 1.	0.487
ATG4B	ATG12	ENSCATP00000018223	ENSCATP00000039750	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.730
ATG4B	ATG3	ENSCATP00000018223	ENSCATP00000043402	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	Autophagy-related protein 3.	0.865