OCA2 protein (Cercocebus atys) - STRING interaction network

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Score

OCA2

OCA2 melanosomal transmembrane protein. (838 aa)

Predicted Functional Partners:

GET3

0.893

ACP1

0.881

ENSCATP00000016899

0.881

SLC45A2

0.795

TYR

0.738

SLC24A5

0.726

CCDC13

0.689

BBS7

0.657

PDE6C

0.653

CEP164

0.644

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACP1	GET3	ENSCATP00000006287	ENSCATP00000002526	LMWPc domain-containing protein.	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	0.881
ACP1	OCA2	ENSCATP00000006287	ENSCATP00000002010	LMWPc domain-containing protein.	OCA2 melanosomal transmembrane protein.	0.881
BBS7	CCDC13	ENSCATP00000008548	ENSCATP00000020679	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	Uncharacterized protein.	0.657
BBS7	CEP164	ENSCATP00000008548	ENSCATP00000025150	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	Centrosomal protein 164.	0.598
BBS7	OCA2	ENSCATP00000008548	ENSCATP00000002010	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	OCA2 melanosomal transmembrane protein.	0.657
BBS7	PDE6C	ENSCATP00000008548	ENSCATP00000011149	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	Phosphodiesterase.	0.816
CCDC13	BBS7	ENSCATP00000020679	ENSCATP00000008548	Uncharacterized protein.	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	0.657
CCDC13	CEP164	ENSCATP00000020679	ENSCATP00000025150	Uncharacterized protein.	Centrosomal protein 164.	0.645
CCDC13	OCA2	ENSCATP00000020679	ENSCATP00000002010	Uncharacterized protein.	OCA2 melanosomal transmembrane protein.	0.689
CCDC13	PDE6C	ENSCATP00000020679	ENSCATP00000011149	Uncharacterized protein.	Phosphodiesterase.	0.653
CEP164	BBS7	ENSCATP00000025150	ENSCATP00000008548	Centrosomal protein 164.	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	0.598
CEP164	CCDC13	ENSCATP00000025150	ENSCATP00000020679	Centrosomal protein 164.	Uncharacterized protein.	0.645
CEP164	OCA2	ENSCATP00000025150	ENSCATP00000002010	Centrosomal protein 164.	OCA2 melanosomal transmembrane protein.	0.644
CEP164	PDE6C	ENSCATP00000025150	ENSCATP00000011149	Centrosomal protein 164.	Phosphodiesterase.	0.587
ENSCATP00000016899	GET3	ENSCATP00000016899	ENSCATP00000002526	LMWPc domain-containing protein.	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	0.881
ENSCATP00000016899	OCA2	ENSCATP00000016899	ENSCATP00000002010	LMWPc domain-containing protein.	OCA2 melanosomal transmembrane protein.	0.881
GET3	ACP1	ENSCATP00000002526	ENSCATP00000006287	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	LMWPc domain-containing protein.	0.881
GET3	ENSCATP00000016899	ENSCATP00000002526	ENSCATP00000016899	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	LMWPc domain-containing protein.	0.881
GET3	OCA2	ENSCATP00000002526	ENSCATP00000002010	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	OCA2 melanosomal transmembrane protein.	0.893
OCA2	ACP1	ENSCATP00000002010	ENSCATP00000006287	OCA2 melanosomal transmembrane protein.	LMWPc domain-containing protein.	0.881