Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
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[Homology]
Score
P2RY2Purinergic receptor P2Y2; Belongs to the G-protein coupled receptor 1 family. (377 aa)    
Predicted Functional Partners:
GNAQ
Uncharacterized protein.
    
 0.940
GNA11
G protein subunit alpha 11.
    
 0.932
P2RY6
Pyrimidinergic receptor P2Y6.
  
 
 
0.930
P2RY12
Purinergic receptor P2Y12.
     
0.905
SFTPC
Surfactant protein C.
     
  0.821
SFTPB
Surfactant protein B.
     
  0.767
PDPK1
3-phosphoinositide dependent protein kinase 1.
     
  0.766
GNB2
G protein subunit beta 2.
    
  0.700
GNG2
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
  0.699
GNB4
G protein subunit beta 4.
    
  0.697
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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