Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RALGAPA1Ral GTPase activating protein catalytic alpha subunit 1. (2452 aa)    
Predicted Functional Partners:
RALGAPB
Ral GTPase activating protein non-catalytic beta subunit.
   
 0.922
NKIRAS2
NFKB inhibitor interacting Ras like 2.
    
 
 0.921
GFOD1
Glucose-fructose oxidoreductase domain containing 1.
    
   0.900
NKIRAS1
NFKB inhibitor interacting Ras like 1.
    
 
 0.788
MEA1
Male-enhanced antigen 1.
    
   0.745
AP2B1
AP complex subunit beta.
    
   0.663
AP2M1
AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]
    
   0.663
ENSCATP00000001208
B2-adapt-app_C domain-containing protein.
    
   0.633
SGIP1
SH3 domain GRB2 like endophilin interacting protein 1.
   
   0.632
GFOD2
Glucose-fructose oxidoreductase domain containing 2.
    
   0.588
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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