ENSCATP00000005000 protein (Cercocebus atys)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ENSCATP00000005000

Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (275 aa)

Predicted Functional Partners:

RNASEH2A

0.802

SETX

0.737

SSBP1

0.716

TYMS

0.715

NADK

0.686

ENSCATP00000036401

0.655

NUDT12

0.641

CDKN1A

0.636

ENSCATP00000000001

0.614

NUDT13

0.614

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDKN1A	ENSCATP00000005000	ENSCATP00000004883	ENSCATP00000005000	Cyclin dependent kinase inhibitor 1A.	Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.636
ENSCATP00000000001	ENSCATP00000005000	ENSCATP00000000001	ENSCATP00000005000	Ig-like domain-containing protein.	Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.614
ENSCATP00000005000	CDKN1A	ENSCATP00000005000	ENSCATP00000004883	Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	Cyclin dependent kinase inhibitor 1A.	0.636
ENSCATP00000005000	ENSCATP00000000001	ENSCATP00000005000	ENSCATP00000000001	Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	Ig-like domain-containing protein.	0.614
ENSCATP00000005000	ENSCATP00000036401	ENSCATP00000005000	ENSCATP00000036401	Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.655
ENSCATP00000005000	NADK	ENSCATP00000005000	ENSCATP00000011305	Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	NAD kinase.	0.686
ENSCATP00000005000	NUDT12	ENSCATP00000005000	ENSCATP00000010573	Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	Nudix hydrolase 12.	0.641
ENSCATP00000005000	NUDT13	ENSCATP00000005000	ENSCATP00000001195	Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	Nudix hydrolase 13.	0.614
ENSCATP00000005000	RNASEH2A	ENSCATP00000005000	ENSCATP00000010655	Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	0.802
ENSCATP00000005000	SETX	ENSCATP00000005000	ENSCATP00000041086	Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	Senataxin.	0.737
ENSCATP00000005000	SSBP1	ENSCATP00000005000	ENSCATP00000023755	Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	Single stranded DNA binding protein 1.	0.716
ENSCATP00000005000	TYMS	ENSCATP00000005000	ENSCATP00000011882	Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	Thymidylate synthetase.	0.715
ENSCATP00000036401	ENSCATP00000005000	ENSCATP00000036401	ENSCATP00000005000	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.655
ENSCATP00000036401	SSBP1	ENSCATP00000036401	ENSCATP00000023755	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	Single stranded DNA binding protein 1.	0.737
NADK	ENSCATP00000005000	ENSCATP00000011305	ENSCATP00000005000	NAD kinase.	Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.686
NUDT12	ENSCATP00000005000	ENSCATP00000010573	ENSCATP00000005000	Nudix hydrolase 12.	Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.641
NUDT12	NUDT13	ENSCATP00000010573	ENSCATP00000001195	Nudix hydrolase 12.	Nudix hydrolase 13.	0.910
NUDT13	ENSCATP00000005000	ENSCATP00000001195	ENSCATP00000005000	Nudix hydrolase 13.	Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.614
NUDT13	NUDT12	ENSCATP00000001195	ENSCATP00000010573	Nudix hydrolase 13.	Nudix hydrolase 12.	0.910
RNASEH2A	ENSCATP00000005000	ENSCATP00000010655	ENSCATP00000005000	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.802