HTR1B protein (Cercocebus atys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

HTR1B

5-hydroxytryptamine receptor 1B. (390 aa)

Predicted Functional Partners:

GNAO1

0.944

GNG2

0.940

GNB4

0.897

GNB1

0.897

GNAI3

0.825

GNAI1

0.825

GNB2

0.800

GNB3

0.799

GNAI2

0.793

GNB5

0.790

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GNAI1	GNAI2	ENSCATP00000019274	ENSCATP00000042164	G protein subunit alpha i1.	G protein subunit alpha i2.	0.993
GNAI1	GNAI3	ENSCATP00000019274	ENSCATP00000013806	G protein subunit alpha i1.	G protein subunit alpha i3.	0.900
GNAI1	GNAO1	ENSCATP00000019274	ENSCATP00000043567	G protein subunit alpha i1.	G protein subunit alpha o1.	0.853
GNAI1	GNB1	ENSCATP00000019274	ENSCATP00000003027	G protein subunit alpha i1.	G protein subunit beta 1.	0.968
GNAI1	GNB2	ENSCATP00000019274	ENSCATP00000032346	G protein subunit alpha i1.	G protein subunit beta 2.	0.964
GNAI1	GNB3	ENSCATP00000019274	ENSCATP00000008249	G protein subunit alpha i1.	G protein subunit beta 3.	0.939
GNAI1	GNB4	ENSCATP00000019274	ENSCATP00000001899	G protein subunit alpha i1.	G protein subunit beta 4.	0.953
GNAI1	GNB5	ENSCATP00000019274	ENSCATP00000006866	G protein subunit alpha i1.	G protein subunit beta 5.	0.888
GNAI1	GNG2	ENSCATP00000019274	ENSCATP00000032086	G protein subunit alpha i1.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.963
GNAI1	HTR1B	ENSCATP00000019274	ENSCATP00000005331	G protein subunit alpha i1.	5-hydroxytryptamine receptor 1B.	0.825
GNAI2	GNAI1	ENSCATP00000042164	ENSCATP00000019274	G protein subunit alpha i2.	G protein subunit alpha i1.	0.993
GNAI2	GNAI3	ENSCATP00000042164	ENSCATP00000013806	G protein subunit alpha i2.	G protein subunit alpha i3.	0.993
GNAI2	GNAO1	ENSCATP00000042164	ENSCATP00000043567	G protein subunit alpha i2.	G protein subunit alpha o1.	0.900
GNAI2	GNB1	ENSCATP00000042164	ENSCATP00000003027	G protein subunit alpha i2.	G protein subunit beta 1.	0.962
GNAI2	GNB2	ENSCATP00000042164	ENSCATP00000032346	G protein subunit alpha i2.	G protein subunit beta 2.	0.981
GNAI2	GNB3	ENSCATP00000042164	ENSCATP00000008249	G protein subunit alpha i2.	G protein subunit beta 3.	0.970
GNAI2	GNB4	ENSCATP00000042164	ENSCATP00000001899	G protein subunit alpha i2.	G protein subunit beta 4.	0.962
GNAI2	GNB5	ENSCATP00000042164	ENSCATP00000006866	G protein subunit alpha i2.	G protein subunit beta 5.	0.896
GNAI2	GNG2	ENSCATP00000042164	ENSCATP00000032086	G protein subunit alpha i2.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.929
GNAI2	HTR1B	ENSCATP00000042164	ENSCATP00000005331	G protein subunit alpha i2.	5-hydroxytryptamine receptor 1B.	0.793