Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MASP1Mannan binding lectin serine peptidase 1; Belongs to the peptidase S1 family. (728 aa)    
Predicted Functional Partners:
MASP2
Mannan binding lectin serine peptidase 2; Belongs to the peptidase S1 family.
  
0.998
MBL2
Mannose binding lectin 2.
   
 0.996
SERPING1
Serpin family G member 1; Belongs to the serpin family.
   
 0.986
FCN3
Ficolin 3.
   
 0.970
COLEC11
Collectin subfamily member 11.
    
 0.957
F2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
   
 
0.911
CFD
Complement factor D; Belongs to the peptidase S1 family.
     
0.907
FCN2
Ficolin 2.
   
 0.867
LOC105580534
Fibrinogen C-terminal domain-containing protein.
   
 0.867
FCN1
Ficolin 1.
   
 0.867
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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