node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PSMB4 | PSMC3 | ENSCATP00000032176 | ENSCATP00000006808 | Proteasome subunit beta; Belongs to the peptidase T1B family. | AAA domain-containing protein; Belongs to the AAA ATPase family. | 0.984 |
PSMB4 | PSMD1 | ENSCATP00000032176 | ENSCATP00000028473 | Proteasome subunit beta; Belongs to the peptidase T1B family. | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. | 0.992 |
PSMB4 | PSMD11 | ENSCATP00000032176 | ENSCATP00000042125 | Proteasome subunit beta; Belongs to the peptidase T1B family. | Proteasome 26S subunit, non-ATPase 11. | 0.997 |
PSMB4 | PSMD12 | ENSCATP00000032176 | ENSCATP00000018222 | Proteasome subunit beta; Belongs to the peptidase T1B family. | Proteasome 26S subunit, non-ATPase 12. | 0.998 |
PSMB4 | PSMD13 | ENSCATP00000032176 | ENSCATP00000038934 | Proteasome subunit beta; Belongs to the peptidase T1B family. | Proteasome 26S subunit, non-ATPase 13. | 0.996 |
PSMB4 | PSMD14 | ENSCATP00000032176 | ENSCATP00000039810 | Proteasome subunit beta; Belongs to the peptidase T1B family. | Proteasome 26S subunit, non-ATPase 14. | 0.997 |
PSMB4 | PSMD2 | ENSCATP00000032176 | ENSCATP00000027748 | Proteasome subunit beta; Belongs to the peptidase T1B family. | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. | 0.990 |
PSMB4 | PSMD3 | ENSCATP00000032176 | ENSCATP00000036678 | Proteasome subunit beta; Belongs to the peptidase T1B family. | Proteasome 26S subunit, non-ATPase 3. | 0.995 |
PSMB4 | PSMD4 | ENSCATP00000032176 | ENSCATP00000013480 | Proteasome subunit beta; Belongs to the peptidase T1B family. | Proteasome 26S subunit, non-ATPase 4. | 0.998 |
PSMB4 | PSMD6 | ENSCATP00000032176 | ENSCATP00000012062 | Proteasome subunit beta; Belongs to the peptidase T1B family. | Proteasome 26S subunit, non-ATPase 6. | 0.998 |
PSMC3 | PSMB4 | ENSCATP00000006808 | ENSCATP00000032176 | AAA domain-containing protein; Belongs to the AAA ATPase family. | Proteasome subunit beta; Belongs to the peptidase T1B family. | 0.984 |
PSMC3 | PSMD1 | ENSCATP00000006808 | ENSCATP00000028473 | AAA domain-containing protein; Belongs to the AAA ATPase family. | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. | 0.984 |
PSMC3 | PSMD11 | ENSCATP00000006808 | ENSCATP00000042125 | AAA domain-containing protein; Belongs to the AAA ATPase family. | Proteasome 26S subunit, non-ATPase 11. | 0.989 |
PSMC3 | PSMD12 | ENSCATP00000006808 | ENSCATP00000018222 | AAA domain-containing protein; Belongs to the AAA ATPase family. | Proteasome 26S subunit, non-ATPase 12. | 0.992 |
PSMC3 | PSMD13 | ENSCATP00000006808 | ENSCATP00000038934 | AAA domain-containing protein; Belongs to the AAA ATPase family. | Proteasome 26S subunit, non-ATPase 13. | 0.987 |
PSMC3 | PSMD14 | ENSCATP00000006808 | ENSCATP00000039810 | AAA domain-containing protein; Belongs to the AAA ATPase family. | Proteasome 26S subunit, non-ATPase 14. | 0.988 |
PSMC3 | PSMD2 | ENSCATP00000006808 | ENSCATP00000027748 | AAA domain-containing protein; Belongs to the AAA ATPase family. | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. | 0.988 |
PSMC3 | PSMD3 | ENSCATP00000006808 | ENSCATP00000036678 | AAA domain-containing protein; Belongs to the AAA ATPase family. | Proteasome 26S subunit, non-ATPase 3. | 0.985 |
PSMC3 | PSMD4 | ENSCATP00000006808 | ENSCATP00000013480 | AAA domain-containing protein; Belongs to the AAA ATPase family. | Proteasome 26S subunit, non-ATPase 4. | 0.988 |
PSMC3 | PSMD6 | ENSCATP00000006808 | ENSCATP00000012062 | AAA domain-containing protein; Belongs to the AAA ATPase family. | Proteasome 26S subunit, non-ATPase 6. | 0.988 |