| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BATF | BATF3 | ENSCATP00000016789 | ENSCATP00000027690 | Basic leucine zipper ATF-like transcription factor. | Basic leucine zipper ATF-like transcription factor 3. | 0.894 |
| BATF | BCL11B | ENSCATP00000016789 | ENSCATP00000037578 | Basic leucine zipper ATF-like transcription factor. | BAF chromatin remodeling complex subunit BCL11B. | 0.497 |
| BATF | CD4 | ENSCATP00000016789 | ENSCATP00000030139 | Basic leucine zipper ATF-like transcription factor. | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | 0.583 |
| BATF | IRF8 | ENSCATP00000016789 | ENSCATP00000008928 | Basic leucine zipper ATF-like transcription factor. | Interferon regulatory factor 8. | 0.489 |
| BATF | SPI1 | ENSCATP00000016789 | ENSCATP00000037330 | Basic leucine zipper ATF-like transcription factor. | Spi-1 proto-oncogene. | 0.459 |
| BATF3 | BATF | ENSCATP00000027690 | ENSCATP00000016789 | Basic leucine zipper ATF-like transcription factor 3. | Basic leucine zipper ATF-like transcription factor. | 0.894 |
| BATF3 | CD4 | ENSCATP00000027690 | ENSCATP00000030139 | Basic leucine zipper ATF-like transcription factor 3. | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | 0.553 |
| BATF3 | IRF8 | ENSCATP00000027690 | ENSCATP00000008928 | Basic leucine zipper ATF-like transcription factor 3. | Interferon regulatory factor 8. | 0.611 |
| BCL11B | BATF | ENSCATP00000037578 | ENSCATP00000016789 | BAF chromatin remodeling complex subunit BCL11B. | Basic leucine zipper ATF-like transcription factor. | 0.497 |
| BCL11B | IRF8 | ENSCATP00000037578 | ENSCATP00000008928 | BAF chromatin remodeling complex subunit BCL11B. | Interferon regulatory factor 8. | 0.516 |
| CD4 | BATF | ENSCATP00000030139 | ENSCATP00000016789 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | Basic leucine zipper ATF-like transcription factor. | 0.583 |
| CD4 | BATF3 | ENSCATP00000030139 | ENSCATP00000027690 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | Basic leucine zipper ATF-like transcription factor 3. | 0.553 |
| CD4 | IFNG | ENSCATP00000030139 | ENSCATP00000022573 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. | 0.995 |
| CD4 | IRF1 | ENSCATP00000030139 | ENSCATP00000025948 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | Interferon regulatory factor. | 0.560 |
| CD4 | IRF8 | ENSCATP00000030139 | ENSCATP00000008928 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | Interferon regulatory factor 8. | 0.524 |
| CD4 | PTPRC | ENSCATP00000030139 | ENSCATP00000008266 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | Protein tyrosine phosphatase receptor type C. | 0.659 |
| CD4 | TRAF6 | ENSCATP00000030139 | ENSCATP00000012971 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | TNF receptor-associated factor 6; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Mediates activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Adapter protein that seems to [...] | 0.580 |
| IFNG | CD4 | ENSCATP00000022573 | ENSCATP00000030139 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | 0.995 |
| IFNG | IRF1 | ENSCATP00000022573 | ENSCATP00000025948 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. | Interferon regulatory factor. | 0.556 |
| IFNG | IRF8 | ENSCATP00000022573 | ENSCATP00000008928 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. | Interferon regulatory factor 8. | 0.496 |