Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PIGLPhosphatidylinositol glycan anchor biosynthesis class L. (252 aa)    
Predicted Functional Partners:
PIGW
Phosphatidylinositol-glycan biosynthesis class W protein; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.
  
 
 0.986
PIGA
Phosphatidylinositol glycan anchor biosynthesis class A.
  
 
 0.976
PIGC
Phosphatidylinositol glycan anchor biosynthesis class C.
     
 0.969
PIGH
Phosphatidylinositol glycan anchor biosynthesis class H.
   
 
 0.962
PIGQ
Phosphatidylinositol glycan anchor biosynthesis class Q.
   
 
 0.944
PIGP
Phosphatidylinositol N-acetylglucosaminyltransferase subunit P; Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.
     
 0.942
DPM2
Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family.
     
 0.942
GPLD1
Glycosylphosphatidylinositol specific phospholipase D1.
     
 0.915
SENP8
SUMO peptidase family member, NEDD8 specific.
    
 0.837
AMDHD2
N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.
    
 0.827
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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