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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMC8Transmembrane channel-like protein. (726 aa)    
Predicted Functional Partners:
KCNG4
Potassium voltage-gated channel modifier subfamily G member 4; Belongs to the potassium channel family.
    
 
 0.639
IMPG1
Interphotoreceptor matrix proteoglycan 1.
     
 0.608
BBS2
Bardet-Biedl syndrome 2 protein homolog.
      
 0.597
SRD5A3
Steroid 5 alpha-reductase 3.
      
 0.591
RGCC
Regulator of cell cycle.
      
 0.591
MYBPC1
Myosin binding protein C, slow type.
    
 0.583
WDR18
WD repeat domain 18.
    
 0.580
SLC30A1
Solute carrier family 30 member 1.
      
 0.535
WNT11
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
   
 
 0.521
IL1A
Interleukin-1 alpha; Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
     
 0.494
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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