STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UGT2A1UDP glucuronosyltransferase family 2 member A1 complex locus; Belongs to the UDP-glycosyltransferase family. (693 aa)    
Predicted Functional Partners:
CYP1B1
Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.
   
 0.672
FANCC
Fanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.
      
 0.644
UGDH
UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
     
 0.628
LOC105584398
Uncharacterized protein.
   
 0.621
COMT
Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.
    
 0.613
CYP19A1
Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family.
   
 0.606
SULT1E1
Sulfotransferase; Belongs to the sulfotransferase 1 family.
   
 
 0.606
LOC105597447
Aldo_ket_red domain-containing protein.
   
 
 0.591
AKR1D1
Aldo-keto reductase family 1 member D1.
   
 
 0.589
HSD17B3
Hydroxysteroid 17-beta dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.588
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.