OGG1 protein (Cercocebus atys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

OGG1

8-oxoguanine DNA glycosylase. (401 aa)

Predicted Functional Partners:

NEIL1

0.854

APEX1

0.845

POLH

0.817

MGMT

0.797

APEX2

0.793

FANCM

0.785

NT5E

0.769

POLI

0.761

SNRPB

0.747

PNP

0.728

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APEX1	APEX2	ENSCATP00000004453	ENSCATP00000044783	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	0.907
APEX1	FANCM	ENSCATP00000004453	ENSCATP00000014720	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	FA complementation group M.	0.650
APEX1	OGG1	ENSCATP00000004453	ENSCATP00000010328	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	8-oxoguanine DNA glycosylase.	0.845
APEX1	POLH	ENSCATP00000004453	ENSCATP00000036973	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	DNA polymerase eta.	0.419
APEX2	APEX1	ENSCATP00000044783	ENSCATP00000004453	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	0.907
APEX2	FANCM	ENSCATP00000044783	ENSCATP00000014720	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	FA complementation group M.	0.650
APEX2	OGG1	ENSCATP00000044783	ENSCATP00000010328	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	8-oxoguanine DNA glycosylase.	0.793
FANCM	APEX1	ENSCATP00000014720	ENSCATP00000004453	FA complementation group M.	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	0.650
FANCM	APEX2	ENSCATP00000014720	ENSCATP00000044783	FA complementation group M.	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	0.650
FANCM	OGG1	ENSCATP00000014720	ENSCATP00000010328	FA complementation group M.	8-oxoguanine DNA glycosylase.	0.785
FANCM	POLH	ENSCATP00000014720	ENSCATP00000036973	FA complementation group M.	DNA polymerase eta.	0.533
FANCM	POLI	ENSCATP00000014720	ENSCATP00000018452	FA complementation group M.	DNA polymerase iota.	0.533
FANCM	SNRPB	ENSCATP00000014720	ENSCATP00000012149	FA complementation group M.	Small nuclear ribonucleoprotein polypeptides B and B1.	0.650
MGMT	OGG1	ENSCATP00000000507	ENSCATP00000010328	O-6-methylguanine-DNA methyltransferase.	8-oxoguanine DNA glycosylase.	0.797
NEIL1	OGG1	ENSCATP00000020297	ENSCATP00000010328	Nei like DNA glycosylase 1.	8-oxoguanine DNA glycosylase.	0.854
NT5E	OGG1	ENSCATP00000025090	ENSCATP00000010328	5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.	8-oxoguanine DNA glycosylase.	0.769
NT5E	PNP	ENSCATP00000025090	ENSCATP00000018291	5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.934
OGG1	APEX1	ENSCATP00000010328	ENSCATP00000004453	8-oxoguanine DNA glycosylase.	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	0.845
OGG1	APEX2	ENSCATP00000010328	ENSCATP00000044783	8-oxoguanine DNA glycosylase.	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	0.793
OGG1	FANCM	ENSCATP00000010328	ENSCATP00000014720	8-oxoguanine DNA glycosylase.	FA complementation group M.	0.785