Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LTC4SLeukotriene C4 synthase. (150 aa)    
Predicted Functional Partners:
ALOX5
Arachidonate 5-lipoxygenase.
    
 0.963
LTA4H
Leukotriene A4 hydrolase.
     
 0.961
GGT5
Gamma-glutamyltransferase 5.
     
 0.920
LOC105599372
Uncharacterized protein.
     
 0.913
GGT1
Uncharacterized protein.
     
 0.913
MGST1
Microsomal glutathione S-transferase 1.
    
 0.702
CYSLTR1
Cysteinyl leukotriene receptor 1.
      
 0.685
ALOX5AP
Arachidonate 5-lipoxygenase activating protein.
   
 0.669
PTGES
Prostaglandin E synthase.
    
 0.662
CYSLTR2
Cysteinyl leukotriene receptor 2.
      
 0.625
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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