Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EN2Homeobox protein engrailed-like. (334 aa)    
Predicted Functional Partners:
HOXD10
Homeobox D10.
   
 
 0.662
EN1
Homeobox protein engrailed-like.
    
   0.611
KLB
Klotho beta.
      
 0.512
FOXA2
Forkhead box A2.
    
 
 0.489
IRX3
Iroquois homeobox 3.
   
 
 0.463
FGF8
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 
 0.454
LMBR1
Limb development membrane protein 1; Belongs to the LIMR family.
      
 0.451
EBF2
EBF transcription factor 2.
      
 0.448
TLE4
TLE family member 4, transcriptional corepressor.
    
   0.431
TLE3
TLE family member 3, transcriptional corepressor.
    
   0.431
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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