STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OTUD7AOTU deubiquitinase 7A. (924 aa)    
Predicted Functional Partners:
UBXN7
UBX domain-containing protein 7.
   
   0.817
TNF
Tumor necrosis factor; Belongs to the tumor necrosis factor family.
   
 0.697
C21orf91
Chromosome 21 open reading frame 91.
      
 0.637
NEURL1
Neuralized E3 ubiquitin protein ligase 1.
    
 
 0.635
SLC25A21
Solute carrier family 25 member 21; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.632
LHFPL4
LHFPL tetraspan subfamily member 4.
   
  
 0.632
CELF6
Uncharacterized protein.
   
  
 0.618
TRAF6
TNF receptor-associated factor 6; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Mediates activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Adapter protein that seems to [...]
    
 0.609
OTUB2
OTU deubiquitinase, ubiquitin aldehyde binding 2.
      
 0.600
UBA52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
 0.592
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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