OTUD7A protein (Cercocebus atys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

OTUD7A

OTU deubiquitinase 7A. (924 aa)

Predicted Functional Partners:

TRAF6

0.745

TRIP12

0.678

UBXN7

0.639

LOC105579396

0.633

ENSCATP00000031033

0.633

ENSCATP00000034768

0.633

ENSCATP00000035134

0.633

RPS27A

0.633

OTULIN

0.620

TNF

0.615

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCATP00000031033	OTUD7A	ENSCATP00000031033	ENSCATP00000010409	Ubiquitin-like domain-containing protein.	OTU deubiquitinase 7A.	0.633
ENSCATP00000031033	OTULIN	ENSCATP00000031033	ENSCATP00000026933	Ubiquitin-like domain-containing protein.	OTU deubiquitinase with linear linkage specificity.	0.811
ENSCATP00000031033	TNF	ENSCATP00000031033	ENSCATP00000001057	Ubiquitin-like domain-containing protein.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.416
ENSCATP00000031033	TRAF6	ENSCATP00000031033	ENSCATP00000012971	Ubiquitin-like domain-containing protein.	TNF receptor-associated factor 6; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Mediates activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Adapter protein that seems to [...]	0.876
ENSCATP00000031033	TRIP12	ENSCATP00000031033	ENSCATP00000015811	Ubiquitin-like domain-containing protein.	Thyroid hormone receptor interactor 12.	0.910
ENSCATP00000031033	UBXN7	ENSCATP00000031033	ENSCATP00000006661	Ubiquitin-like domain-containing protein.	UBX domain-containing protein 7.	0.880
ENSCATP00000034768	OTUD7A	ENSCATP00000034768	ENSCATP00000010409	Ubiquitin-like domain-containing protein.	OTU deubiquitinase 7A.	0.633
ENSCATP00000034768	OTULIN	ENSCATP00000034768	ENSCATP00000026933	Ubiquitin-like domain-containing protein.	OTU deubiquitinase with linear linkage specificity.	0.797
ENSCATP00000034768	TNF	ENSCATP00000034768	ENSCATP00000001057	Ubiquitin-like domain-containing protein.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.416
ENSCATP00000034768	TRAF6	ENSCATP00000034768	ENSCATP00000012971	Ubiquitin-like domain-containing protein.	TNF receptor-associated factor 6; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Mediates activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Adapter protein that seems to [...]	0.857
ENSCATP00000034768	TRIP12	ENSCATP00000034768	ENSCATP00000015811	Ubiquitin-like domain-containing protein.	Thyroid hormone receptor interactor 12.	0.910
ENSCATP00000034768	UBXN7	ENSCATP00000034768	ENSCATP00000006661	Ubiquitin-like domain-containing protein.	UBX domain-containing protein 7.	0.880
ENSCATP00000035134	OTUD7A	ENSCATP00000035134	ENSCATP00000010409	Ubiquitin-like domain-containing protein.	OTU deubiquitinase 7A.	0.633
ENSCATP00000035134	OTULIN	ENSCATP00000035134	ENSCATP00000026933	Ubiquitin-like domain-containing protein.	OTU deubiquitinase with linear linkage specificity.	0.811
ENSCATP00000035134	TNF	ENSCATP00000035134	ENSCATP00000001057	Ubiquitin-like domain-containing protein.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.416
ENSCATP00000035134	TRAF6	ENSCATP00000035134	ENSCATP00000012971	Ubiquitin-like domain-containing protein.	TNF receptor-associated factor 6; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Mediates activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Adapter protein that seems to [...]	0.876
ENSCATP00000035134	TRIP12	ENSCATP00000035134	ENSCATP00000015811	Ubiquitin-like domain-containing protein.	Thyroid hormone receptor interactor 12.	0.910
ENSCATP00000035134	UBXN7	ENSCATP00000035134	ENSCATP00000006661	Ubiquitin-like domain-containing protein.	UBX domain-containing protein 7.	0.880
LOC105579396	OTUD7A	ENSCATP00000007127	ENSCATP00000010409	Ubiquitin-like domain-containing protein.	OTU deubiquitinase 7A.	0.633
LOC105579396	OTULIN	ENSCATP00000007127	ENSCATP00000026933	Ubiquitin-like domain-containing protein.	OTU deubiquitinase with linear linkage specificity.	0.811