Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
co-expression
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[Homology]
Score
NUDT12Nudix hydrolase 12. (462 aa)    
Predicted Functional Partners:
NADSYN1
Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.
  
 
 0.975
NT5E
5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.
    
  0.974
NT5M
5',3'-nucleotidase, mitochondrial.
     
  0.956
NT5C1A
5'-nucleotidase, cytosolic IA.
    
 0.923
NT5C2
5'-nucleotidase, cytosolic II.
     
 0.920
SIRT5
NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinyl [...]
   
 0.915
NT5C1B
Uncharacterized protein.
    
 0.915
SIRT1
Sirtuin 1.
   
 0.915
ENSCATP00000002408
Uncharacterized protein.
    
 
 0.914
SIRT2
NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.
   
  0.912
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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