STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERBB3Erb-b2 receptor tyrosine kinase 3. (1349 aa)    
Predicted Functional Partners:
ERBB2
Receptor protein-tyrosine kinase.
  
 
0.995
NRG1
Neuregulin 1.
    
 0.987
EGFR
Receptor protein-tyrosine kinase.
  
 
0.985
GRB2
Growth factor receptor bound protein 2.
    
 0.971
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.969
EGF
Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.
   
 0.960
NRG2
Neuregulin 2.
    
 0.955
TGFA
Transforming growth factor alpha.
    
 0.951
EREG
Epiregulin.
    
 0.943
MET
MET proto-oncogene, receptor tyrosine kinase.
   
0.933
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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