Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
C16orf74Chromosome 16 open reading frame 74. (76 aa)    
Predicted Functional Partners:
PPP3CA
Serine/threonine-protein phosphatase.
    
 
 0.901
EMC1
ER membrane protein complex subunit 1.
    
 
 0.858
UNC119
Unc-119 lipid binding chaperone.
    
   0.847
EMC3
ER membrane protein complex subunit 3; Belongs to the EMC3 family.
   
 
 0.781
EMC2
ER membrane protein complex subunit 2.
   
 
 0.781
EMC7
ER membrane protein complex subunit 7.
   
 
 0.773
EMC10
ER membrane protein complex subunit 10.
    
 
 0.767
EMC4
ER membrane protein complex subunit 4; Belongs to the EMC4 family.
   
 
 0.757
EMC6
ER membrane protein complex subunit 6.
   
 
 0.733
MMGT1
Membrane magnesium transporter 1.
    
 
 0.695
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
Server load: low (16%) [HD]