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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRDM1PR/SET domain 1. (825 aa)    
Predicted Functional Partners:
HDAC2
Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
    
 0.766
EHMT2
Euchromatic histone lysine methyltransferase 2.
    
 0.656
STAT3
Signal transducer and activator of transcription.
   
 
 0.605
SOX17
SRY-box transcription factor 17.
    
 
 0.581
TFAP2C
Transcription factor AP-2 gamma.
      
 0.568
CMIP
C-Maf inducing protein.
      
 0.557
NDNF
Neuron derived neurotrophic factor.
      
 0.557
DAZL
Deleted in azoospermia like.
      
 0.555
EVC2
EvC ciliary complex subunit 2.
      
 0.555
SHARPIN
SHANK associated RH domain interactor.
      
 0.553
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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