Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HDHD5Haloacid dehalogenase like hydrolase domain containing 5. (423 aa)    
Predicted Functional Partners:
PDK3
Protein-serine/threonine kinase.
   
   0.863
TCEANC2
Transcription elongation factor A N-terminal and central domain containing 2.
      
 0.641
ISY1
Uncharacterized protein.
      
 0.598
PDK4
Protein-serine/threonine kinase.
   
   0.566
PDK2
Protein-serine/threonine kinase.
   
   0.566
PDK1
Protein-serine/threonine kinase.
   
   0.566
UQCRC1
Ubiquinol-cytochrome c reductase core protein 1.
   
  
 0.557
ADA2
Adenosine deaminase 2.
     
 0.552
PNP
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
    
 0.509
PSMA6
Proteasome subunit alpha type.
    
   0.471
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
Server load: low (32%) [HD]