KCTD8 protein (Cercocebus atys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

KCTD8

Potassium channel tetramerization domain containing 8. (473 aa)

Predicted Functional Partners:

KCTD16

0.777

GNG2

0.760

SOHLH1

0.751

CUL3

0.716

GABBR2

0.675

RND2

0.589

ZFP69B

0.559

GNB4

0.553

GNB1

0.553

GABBR1

0.530

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUL3	GNB1	ENSCATP00000032149	ENSCATP00000003027	Cullin 3; Belongs to the cullin family.	G protein subunit beta 1.	0.501
CUL3	GNB4	ENSCATP00000032149	ENSCATP00000001899	Cullin 3; Belongs to the cullin family.	G protein subunit beta 4.	0.501
CUL3	GNG2	ENSCATP00000032149	ENSCATP00000032086	Cullin 3; Belongs to the cullin family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.644
CUL3	KCTD16	ENSCATP00000032149	ENSCATP00000040789	Cullin 3; Belongs to the cullin family.	Potassium channel tetramerization domain containing 16.	0.711
CUL3	KCTD8	ENSCATP00000032149	ENSCATP00000010677	Cullin 3; Belongs to the cullin family.	Potassium channel tetramerization domain containing 8.	0.716
GABBR1	GABBR2	ENSCATP00000008314	ENSCATP00000011033	Gamma-aminobutyric acid type B receptor subunit 1.	Gamma-aminobutyric acid type B receptor subunit 2.	0.999
GABBR1	GNB1	ENSCATP00000008314	ENSCATP00000003027	Gamma-aminobutyric acid type B receptor subunit 1.	G protein subunit beta 1.	0.827
GABBR1	GNB4	ENSCATP00000008314	ENSCATP00000001899	Gamma-aminobutyric acid type B receptor subunit 1.	G protein subunit beta 4.	0.827
GABBR1	GNG2	ENSCATP00000008314	ENSCATP00000032086	Gamma-aminobutyric acid type B receptor subunit 1.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.836
GABBR1	KCTD16	ENSCATP00000008314	ENSCATP00000040789	Gamma-aminobutyric acid type B receptor subunit 1.	Potassium channel tetramerization domain containing 16.	0.530
GABBR1	KCTD8	ENSCATP00000008314	ENSCATP00000010677	Gamma-aminobutyric acid type B receptor subunit 1.	Potassium channel tetramerization domain containing 8.	0.530
GABBR2	GABBR1	ENSCATP00000011033	ENSCATP00000008314	Gamma-aminobutyric acid type B receptor subunit 2.	Gamma-aminobutyric acid type B receptor subunit 1.	0.999
GABBR2	GNB1	ENSCATP00000011033	ENSCATP00000003027	Gamma-aminobutyric acid type B receptor subunit 2.	G protein subunit beta 1.	0.853
GABBR2	GNB4	ENSCATP00000011033	ENSCATP00000001899	Gamma-aminobutyric acid type B receptor subunit 2.	G protein subunit beta 4.	0.855
GABBR2	GNG2	ENSCATP00000011033	ENSCATP00000032086	Gamma-aminobutyric acid type B receptor subunit 2.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.887
GABBR2	KCTD16	ENSCATP00000011033	ENSCATP00000040789	Gamma-aminobutyric acid type B receptor subunit 2.	Potassium channel tetramerization domain containing 16.	0.904
GABBR2	KCTD8	ENSCATP00000011033	ENSCATP00000010677	Gamma-aminobutyric acid type B receptor subunit 2.	Potassium channel tetramerization domain containing 8.	0.675
GNB1	CUL3	ENSCATP00000003027	ENSCATP00000032149	G protein subunit beta 1.	Cullin 3; Belongs to the cullin family.	0.501
GNB1	GABBR1	ENSCATP00000003027	ENSCATP00000008314	G protein subunit beta 1.	Gamma-aminobutyric acid type B receptor subunit 1.	0.827
GNB1	GABBR2	ENSCATP00000003027	ENSCATP00000011033	G protein subunit beta 1.	Gamma-aminobutyric acid type B receptor subunit 2.	0.853