Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACTA1Actin alpha 1, skeletal muscle. (377 aa)    
Predicted Functional Partners:
ACTC1
Actin alpha cardiac muscle 1.
  
 
0.989
ACTG2
Actin gamma 2, smooth muscle.
   
 
 0.985
ACTBL2
Actin beta like 2.
   
   0.979
ACTB
Uncharacterized protein.
   
   0.960
ENSCATP00000019657
Uncharacterized protein; Belongs to the actin family.
   
   0.960
ENSCATP00000039367
Uncharacterized protein.
   
   0.960
ENSCATP00000027886
Uncharacterized protein.
   
  0.958
MYBPC3
Myosin binding protein C, cardiac.
   
 0.908
GSN
Gelsolin.
   
 0.907
MYL2
Myosin light chain 2.
   
 0.903
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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