Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa)    
Predicted Functional Partners:
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
   
 0.999
ITGB7
Integrin beta; Belongs to the integrin beta chain family.
   
 0.999
VCAM1
Vascular cell adhesion molecule 1.
    
 0.988
PXN
Paxillin.
    
 0.970
ITGB2
Integrin beta.
   
 0.969
PTK2
Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.966
SPP1
Secreted phosphoprotein 1.
   
 0.963
JAM2
Junctional adhesion molecule 2.
     
 0.958
PTK2B
Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.953
ITGA5
Integrin subunit alpha 5; Belongs to the integrin alpha chain family.
    
0.944
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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