Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
GCHFRGTP cyclohydrolase I feedback regulator. (84 aa)    
Predicted Functional Partners:
GCH1
GTP cyclohydrolase 1.
    
 0.992
PTS
6-pyruvoyl tetrahydrobiopterin synthase.
     
 0.861
EXD1
Exonuclease 3'-5' domain containing 1.
      
 0.612
SPR
Sepiapterin reductase.
      
 0.585
SURF1
SURF1-like protein; Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. Belongs to the SURF1 family.
   
 
  0.574
DNAJC12
DnaJ heat shock protein family (Hsp40) member C12.
      
 0.545
QDPR
Quinoid dihydropteridine reductase.
   
  
 0.541
DTYMK
Deoxythymidylate kinase.
      
 0.511
WAS
WASP actin nucleation promoting factor.
      
 0.503
MNAT1
CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.
      
 0.500
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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