Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
RAB25RAB25, member RAS oncogene family. (185 aa)    
Predicted Functional Partners:
RAB11FIP2
RAB11 family interacting protein 2.
   
 0.908
RAB11FIP5
Uncharacterized protein.
    
 
 0.890
RAB11FIP1
RAB11 family interacting protein 1.
   
 0.847
RAB11FIP3
RAB11 family interacting protein 3.
    
 0.786
RAB11FIP4
RAB11 family interacting protein 4.
    
 0.778
ESRP1
Epithelial splicing regulatory protein 1.
   
  
 0.759
EXOC2
Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.
    
 0.736
KRTCAP3
Keratinocyte associated protein 3.
   
  
 0.735
CHM
Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
    
 0.709
RAB3IP
RAB3A interacting protein.
    
 0.691
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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