LOC105599862 protein (Cercocebus atys) - STRING interaction network

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LOC105599862

Nudix hydrolase domain-containing protein. (188 aa)

Predicted Functional Partners:

NADSYN1

0.684

GCH1

0.677

FPGS

0.663

QPRT

0.655

TYMS

0.640

MROH6

0.622

NAPRT

0.622

GLDC

0.620

RRM1

0.619

NT5E

0.616

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FPGS	GCH1	ENSCATP00000002576	ENSCATP00000003724	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	GTP cyclohydrolase 1.	0.792
FPGS	LOC105599862	ENSCATP00000002576	ENSCATP00000010868	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	Nudix hydrolase domain-containing protein.	0.663
FPGS	TYMS	ENSCATP00000002576	ENSCATP00000011882	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	Thymidylate synthetase.	0.861
GCH1	FPGS	ENSCATP00000003724	ENSCATP00000002576	GTP cyclohydrolase 1.	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	0.792
GCH1	LOC105599862	ENSCATP00000003724	ENSCATP00000010868	GTP cyclohydrolase 1.	Nudix hydrolase domain-containing protein.	0.677
GLDC	LOC105599862	ENSCATP00000034232	ENSCATP00000010868	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.	Nudix hydrolase domain-containing protein.	0.620
GLDC	TYMS	ENSCATP00000034232	ENSCATP00000011882	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.	Thymidylate synthetase.	0.840
LOC105599862	FPGS	ENSCATP00000010868	ENSCATP00000002576	Nudix hydrolase domain-containing protein.	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	0.663
LOC105599862	GCH1	ENSCATP00000010868	ENSCATP00000003724	Nudix hydrolase domain-containing protein.	GTP cyclohydrolase 1.	0.677
LOC105599862	GLDC	ENSCATP00000010868	ENSCATP00000034232	Nudix hydrolase domain-containing protein.	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.	0.620
LOC105599862	MROH6	ENSCATP00000010868	ENSCATP00000008190	Nudix hydrolase domain-containing protein.	Maestro heat like repeat family member 6.	0.622
LOC105599862	NADSYN1	ENSCATP00000010868	ENSCATP00000012969	Nudix hydrolase domain-containing protein.	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.	0.684
LOC105599862	NAPRT	ENSCATP00000010868	ENSCATP00000016089	Nudix hydrolase domain-containing protein.	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	0.622
LOC105599862	NT5E	ENSCATP00000010868	ENSCATP00000025090	Nudix hydrolase domain-containing protein.	5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.	0.616
LOC105599862	QPRT	ENSCATP00000010868	ENSCATP00000019229	Nudix hydrolase domain-containing protein.	Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family.	0.655
LOC105599862	RRM1	ENSCATP00000010868	ENSCATP00000023327	Nudix hydrolase domain-containing protein.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.619
LOC105599862	TYMS	ENSCATP00000010868	ENSCATP00000011882	Nudix hydrolase domain-containing protein.	Thymidylate synthetase.	0.640
MROH6	LOC105599862	ENSCATP00000008190	ENSCATP00000010868	Maestro heat like repeat family member 6.	Nudix hydrolase domain-containing protein.	0.622
MROH6	NADSYN1	ENSCATP00000008190	ENSCATP00000012969	Maestro heat like repeat family member 6.	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.	0.720
MROH6	QPRT	ENSCATP00000008190	ENSCATP00000019229	Maestro heat like repeat family member 6.	Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family.	0.760