STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LDLRAP1Low density lipoprotein receptor adaptor protein 1. (308 aa)    
Predicted Functional Partners:
LDLR
Low density lipoprotein receptor.
    
 0.980
ITSN2
Intersectin 2.
    
  0.942
LRP2
LDL receptor related protein 2.
    
 0.934
AP2B1
AP complex subunit beta.
    
 0.928
ENSCATP00000001208
B2-adapt-app_C domain-containing protein.
    
 0.900
APOB
Apolipoprotein B.
     
 0.845
AP1B1
AP complex subunit beta.
    
 0.834
DAB2
DAB adaptor protein 2.
     
0.828
VLDLR
Very low density lipoprotein receptor.
    
 0.825
LRP6
Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.
    
 0.824
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.