Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PDE6CPhosphodiesterase. (858 aa)    
Predicted Functional Partners:
PDE6G
Phosphodiesterase 6G.
   
 0.922
GMPS
Guanine monophosphate synthase.
     
  0.900
HPRT1
Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
     
  0.900
GUCY2D
Guanylate cyclase.
   
 0.844
GUCY2C
Guanylate cyclase.
    
 0.841
GNAT2
G protein subunit alpha transducin 2.
   
 
 0.827
GUCY2F
Guanylate cyclase.
   
 0.818
GUCY1B1
Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
   
 0.808
NPR2
Guanylate cyclase.
    
 0.790
NT5E
5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.
     
 0.790
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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