STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
XIAPX-linked inhibitor of apoptosis. (497 aa)    
Predicted Functional Partners:
DIABLO
Uncharacterized protein.
    
 0.999
ENSCATP00000002218
Uncharacterized protein.
    
 0.996
CASP9
Caspase 9; Belongs to the peptidase C14A family.
   
 0.996
CASP7
Caspase 7; Belongs to the peptidase C14A family.
   
 0.994
RIPK2
Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.
   
 0.992
CASP3
Uncharacterized protein; Belongs to the peptidase C14A family.
   
 0.988
HTRA2
HtrA serine peptidase 2.
    
 0.988
ENSCATP00000038453
Uncharacterized protein; Belongs to the peptidase C14A family.
   
 0.988
BIRC2
Baculoviral IAP repeat containing 2.
    
0.978
SEPTIN4
Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
    
 0.977
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.