Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LGI4Leucine rich repeat LGI family member 4. (537 aa)    
Predicted Functional Partners:
ADAM22
ADAM metallopeptidase domain 22.
     
 0.765
ADAM11
ADAM metallopeptidase domain 11.
     
 0.730
ADAM23
ADAM metallopeptidase domain 23.
     
 0.670
PRAG1
PEAK1 related, kinase-activating pseudokinase 1.
      
 0.518
MPZ
Myelin protein zero.
      
 0.499
GPSM1
G protein signaling modulator 1.
      
 0.498
SEMA4F
Ssemaphorin 4F; Belongs to the semaphorin family.
      
 0.498
PRKCG
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
      
 0.497
SEMA4G
Semaphorin 4G; Belongs to the semaphorin family.
      
 0.497
PPP2R5B
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
      
 0.497
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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