STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP3K3Mitogen-activated protein kinase kinase kinase 3. (657 aa)    
Predicted Functional Partners:
MAP2K5
Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily.
  
0.992
CCM2
CCM2 scaffold protein.
    
 0.943
MAP2K3
Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.
  
0.924
PAK1
Non-specific serine/threonine protein kinase.
    
0.918
SQSTM1
Sequestosome 1.
    
 0.915
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
  
0.915
MAP2K6
Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily.
  
0.915
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
   
0.914
PAK2
Non-specific serine/threonine protein kinase.
  
 
0.914
IKBKG
Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.
    
 0.912
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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