ITFG2 protein (Cercocebus atys) - STRING interaction network

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Score

ITFG2

Integrin alpha FG-GAP repeat containing 2. (447 aa)

Predicted Functional Partners:

KPTN

0.997

C12orf66

0.997

DEPDC5

0.983

NPRL2

0.982

WDR24

0.976

WDR59

0.975

DMRTC2

0.948

LAMP1

0.917

BMT2

0.903

NPRL3

0.835

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMT2	C12orf66	ENSCATP00000035599	ENSCATP00000037722	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Chromosome 12 open reading frame 66.	0.940
BMT2	DEPDC5	ENSCATP00000035599	ENSCATP00000020322	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	DEP domain-containing protein.	0.921
BMT2	ITFG2	ENSCATP00000035599	ENSCATP00000019893	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Integrin alpha FG-GAP repeat containing 2.	0.903
BMT2	KPTN	ENSCATP00000035599	ENSCATP00000015146	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Kaptin, actin binding protein.	0.834
BMT2	NPRL2	ENSCATP00000035599	ENSCATP00000030113	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	NPR2 like, GATOR1 complex subunit.	0.856
BMT2	NPRL3	ENSCATP00000035599	ENSCATP00000024728	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	NPR3 like, GATOR1 complex subunit.	0.819
BMT2	WDR24	ENSCATP00000035599	ENSCATP00000044750	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	WD repeat domain 24.	0.434
BMT2	WDR59	ENSCATP00000035599	ENSCATP00000019922	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	WD repeat domain 59.	0.429
C12orf66	BMT2	ENSCATP00000037722	ENSCATP00000035599	Chromosome 12 open reading frame 66.	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	0.940
C12orf66	DEPDC5	ENSCATP00000037722	ENSCATP00000020322	Chromosome 12 open reading frame 66.	DEP domain-containing protein.	0.980
C12orf66	ITFG2	ENSCATP00000037722	ENSCATP00000019893	Chromosome 12 open reading frame 66.	Integrin alpha FG-GAP repeat containing 2.	0.997
C12orf66	KPTN	ENSCATP00000037722	ENSCATP00000015146	Chromosome 12 open reading frame 66.	Kaptin, actin binding protein.	0.995
C12orf66	NPRL2	ENSCATP00000037722	ENSCATP00000030113	Chromosome 12 open reading frame 66.	NPR2 like, GATOR1 complex subunit.	0.973
C12orf66	NPRL3	ENSCATP00000037722	ENSCATP00000024728	Chromosome 12 open reading frame 66.	NPR3 like, GATOR1 complex subunit.	0.783
C12orf66	WDR24	ENSCATP00000037722	ENSCATP00000044750	Chromosome 12 open reading frame 66.	WD repeat domain 24.	0.975
C12orf66	WDR59	ENSCATP00000037722	ENSCATP00000019922	Chromosome 12 open reading frame 66.	WD repeat domain 59.	0.976
DEPDC5	BMT2	ENSCATP00000020322	ENSCATP00000035599	DEP domain-containing protein.	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	0.921
DEPDC5	C12orf66	ENSCATP00000020322	ENSCATP00000037722	DEP domain-containing protein.	Chromosome 12 open reading frame 66.	0.980
DEPDC5	DMRTC2	ENSCATP00000020322	ENSCATP00000029445	DEP domain-containing protein.	DMRT like family C2.	0.920
DEPDC5	ITFG2	ENSCATP00000020322	ENSCATP00000019893	DEP domain-containing protein.	Integrin alpha FG-GAP repeat containing 2.	0.983