NPC1L1 protein (Cercocebus atys) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

NPC1L1

NPC1 like intracellular cholesterol transporter 1. (1356 aa)

Predicted Functional Partners:

NPC2

0.958

SREBF2

0.883

SREBF1

0.878

MYCN

0.827

INSIG1

0.742

INSIG2

0.742

OSBPL5

0.735

ABCG5

0.725

LOC105590576

0.720

ABCA1

0.618

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA1	INSIG1	ENSCATP00000021872	ENSCATP00000029128	ATP binding cassette subfamily A member 1.	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	0.557
ABCA1	NPC1L1	ENSCATP00000021872	ENSCATP00000022324	ATP binding cassette subfamily A member 1.	NPC1 like intracellular cholesterol transporter 1.	0.618
ABCA1	SREBF1	ENSCATP00000021872	ENSCATP00000037484	ATP binding cassette subfamily A member 1.	Sterol regulatory element binding transcription factor 1.	0.481
ABCA1	SREBF2	ENSCATP00000021872	ENSCATP00000026884	ATP binding cassette subfamily A member 1.	Sterol regulatory element binding transcription factor 2.	0.568
ABCG5	LOC105590576	ENSCATP00000024031	ENSCATP00000007558	ATP binding cassette subfamily G member 5.	ABC2_membrane domain-containing protein.	0.999
ABCG5	NPC1L1	ENSCATP00000024031	ENSCATP00000022324	ATP binding cassette subfamily G member 5.	NPC1 like intracellular cholesterol transporter 1.	0.725
ABCG5	SREBF2	ENSCATP00000024031	ENSCATP00000026884	ATP binding cassette subfamily G member 5.	Sterol regulatory element binding transcription factor 2.	0.483
INSIG1	ABCA1	ENSCATP00000029128	ENSCATP00000021872	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	ATP binding cassette subfamily A member 1.	0.557
INSIG1	INSIG2	ENSCATP00000029128	ENSCATP00000035306	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	0.446
INSIG1	NPC1L1	ENSCATP00000029128	ENSCATP00000022324	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	NPC1 like intracellular cholesterol transporter 1.	0.742
INSIG1	SREBF1	ENSCATP00000029128	ENSCATP00000037484	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	Sterol regulatory element binding transcription factor 1.	0.555
INSIG1	SREBF2	ENSCATP00000029128	ENSCATP00000026884	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	Sterol regulatory element binding transcription factor 2.	0.726
INSIG2	INSIG1	ENSCATP00000035306	ENSCATP00000029128	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	0.446
INSIG2	NPC1L1	ENSCATP00000035306	ENSCATP00000022324	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	NPC1 like intracellular cholesterol transporter 1.	0.742
INSIG2	SREBF1	ENSCATP00000035306	ENSCATP00000037484	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	Sterol regulatory element binding transcription factor 1.	0.545
INSIG2	SREBF2	ENSCATP00000035306	ENSCATP00000026884	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	Sterol regulatory element binding transcription factor 2.	0.687
LOC105590576	ABCG5	ENSCATP00000007558	ENSCATP00000024031	ABC2_membrane domain-containing protein.	ATP binding cassette subfamily G member 5.	0.999
LOC105590576	NPC1L1	ENSCATP00000007558	ENSCATP00000022324	ABC2_membrane domain-containing protein.	NPC1 like intracellular cholesterol transporter 1.	0.720
LOC105590576	SREBF2	ENSCATP00000007558	ENSCATP00000026884	ABC2_membrane domain-containing protein.	Sterol regulatory element binding transcription factor 2.	0.483
MYCN	NPC1L1	ENSCATP00000036767	ENSCATP00000022324	MYCN proto-oncogene, bHLH transcription factor.	NPC1 like intracellular cholesterol transporter 1.	0.827