STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC105572468LYR motif containing 4; Belongs to the complex I LYR family. (130 aa)    
Predicted Functional Partners:
NFS1
Aminotran_5 domain-containing protein.
   
 0.998
FXN
Frataxin.
    
 0.994
ISCU
Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.
    
 0.993
SCLY
Selenocysteine lyase.
   
 0.931
NDUFAB1
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
    
 
 0.912
PALB2
Partner and localizer of BRCA2.
    
 
 0.882
PPP1R15A
Protein phosphatase 1 regulatory subunit 15A.
   
 0.867
R3HDM4
R3H domain containing 4.
   
 0.867
GTSE1
G2 and S-phase expressed 1.
   
 0.867
FDX2
2Fe-2S ferredoxin-type domain-containing protein.
   
 0.806
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.