STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARRDC5Arrestin domain containing 5. (319 aa)    
Predicted Functional Partners:
NEDD4
NEDD4 E3 ubiquitin protein ligase.
    
 
 0.617
WWP2
E3 ubiquitin-protein ligase.
    
 
 0.616
ZNRF1
Zinc and ring finger 1.
      
 0.502
NEDD4L
NEDD4 like E3 ubiquitin protein ligase.
    
 
 0.499
VPS26C
VPS26 endosomal protein sorting factor C.
      
 0.485
TXN2
Thioredoxin 2.
    
 0.482
TNFRSF1B
TNF receptor superfamily member 1B.
      
 0.481
TXNIP
Thioredoxin interacting protein.
      
 0.480
LOC105583545
E3 ubiquitin-protein ligase.
    
 
 0.456
WWP1
E3 ubiquitin-protein ligase.
    
 
 0.456
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.