STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MLF1Myeloid leukemia factor 1. (298 aa)    
Predicted Functional Partners:
YWHAE
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family.
    
 
 0.889
ENSCATP00000040576
14_3_3 domain-containing protein; Belongs to the 14-3-3 family.
    
 
 0.841
HACE1
HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1.
      
 0.702
VRK1
VRK serine/threonine kinase 1; Belongs to the protein kinase superfamily.
      
 0.565
BAZ1A
Bromodomain adjacent to zinc finger domain 1A.
      
 0.561
CENPU
Centromere protein U.
    
 
 0.510
CCDC153
Coiled-coil domain containing 153.
      
 0.482
MFSD1
Major facilitator superfamily domain containing 1.
      
 0.479
GFM1
Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mito [...]
      
 0.477
ADAM23
ADAM metallopeptidase domain 23.
   
  
 0.477
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.