STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UBE2WUBIQUITIN_CONJUGAT_2 domain-containing protein. (191 aa)    
Predicted Functional Partners:
ENSCATP00000001061
UBIQUITIN_CONJUGAT_2 domain-containing protein.
   
 0.989
LOC105581053
UBIQUITIN_CONJUGAT_2 domain-containing protein.
   
 0.989
UBE2H
Ubiquitin conjugating enzyme E2 H; Belongs to the ubiquitin-conjugating enzyme family.
   
 
 0.910
TRIP12
Thyroid hormone receptor interactor 12.
    
 0.891
ATG7
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]
    
 0.886
UBA3
Ubiquitin like modifier activating enzyme 3.
    
 0.886
UBA1
Ubiquitin like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family.
    
 0.870
UBA5
Ubiquitin like modifier activating enzyme 5.
    
 0.845
UBE2J1
Ubiquitin conjugating enzyme E2 J1.
     
 0.820
STUB1
STIP1 homology and U-box containing protein 1.
    
 0.793
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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