Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DOCK3Dedicator of cytokinesis 3; Belongs to the DOCK family. (2035 aa)    
Predicted Functional Partners:
ELMO1
Engulfment and cell motility 1.
  
 0.958
ELMO3
Engulfment and cell motility 3.
   
 0.949
ELMO2
Engulfment and cell motility 2.
   
 0.870
DOCK4
Dedicator of cytokinesis 4; Belongs to the DOCK family.
   
 0.806
CRK
CRK proto-oncogene, adaptor protein.
    
 0.781
CRKL
CRK like proto-oncogene, adaptor protein.
    
 0.777
RHOG
Ras homolog gene family, member G.
   
 0.656
ENSMFAP00000017276
Uncharacterized protein.
   
 0.656
ABI1
Abl interactor 1.
     
 0.639
SLC9A9
Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
   
  
 0.619
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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